please I need some help with my Border Collie?

[Jo CIMDA]

Hi Leandre

Elevated CPK and AST is seen in muscle disease so perhaps this can be further investigated.  On this basis I looked up 'exercise intolerance' in a vet book that I have (Notes on Canine Internal Medicine by Hall, Murphy and Darke)   It may or may not be relevant to Nina, but you would know. The following are listed as common causes.  I won't list the uncommon ones unless you want them. 


Definition:  Reduced ability to exercise, decreased stamina, reluctance to exercise.

Clinical signs:  Muscle weakness/wasting, Musculoskeletal pain, panting/tachypnoea (rapid, shallow breathing),prolonged recovery from exercise, high temperature, reduced stamina at exercise, reluctance to exercise.

Common causes:

Cardiac disease

Endocrine disease (hypothyroidism, Addison's)

Generalised weakness: Anaemia, chronic inflammation or infection or wasting, drugs, Neoplasia, Nutritional deficiency, obesity, parasitism, pyrexia (High temperature).

Metabolic disease:
hypercalcaemia (high calcium)
hypo/hyperKalaemia (high or low potassium)
hyponatraemia (low sodium)

Muscular disease:
myopathies

Neurological/spinal disease
Cervical spondylopathy
Intervertebral disc protrusion
Vestibular disease

Neuromuscular disease
Myasthenia gravis

I have known a bearded collie to be excercise intolerant - in so many ways he looked and behaved very normal but the day after exercise he had these 'episodes' .  He had extensive tests at Bristol University and they diagnosed a problems with lactic acid affecting his heart muscles. I can't remember name of the condition specifically diagnosed in his case. 

There is a condition called exertional rhabdomyolysis. It can be minor or extreme. Again it involves lactic acidosis.   Penel's dog had this so she may be able to help further.

This meant to be nothing more than food for thought.

Jo

[leandrenina]

Thanks. I will look into the info you gave. Although the signs aren't really what she displays like  Muscle weakness/wasting, there's nothing wrong with her muscles she have good muscles mass on her hind legs.  No signs of Musculoskeletal pain, panting is quite normal after exercise ,high temperature,  she only had that when she had the nasty infection reduced stamina at exercise, she is always ready to go and can't wait for play time and don't stop unless I stop so I don't think reluctance to exercise is in play here.

[leandrenina]

Hi Jo

It seems like it turned out to be a absorption problem. I did some further tests and they found a very low amount of Vit B12 in her blood. She's been getting Vit B12 shots the last 2 weeks and it seems to make a difference. Do you have any knowledge of something like this.

[Jo CIMDA]

Hi Leandre

Is Nina anaemic?

Jo

[leandrenina]

Hi every one. I'm glad to say that I found Nina's problem at last. Its been 5 months already and she hasn't had any problems so far. Just thought I would give you an update. She now get a Vit B12 shot every week and problem solved. This is what I found out after I took her for some more tests. https://www.animalgenetics.us/Canine/Genetic_Disease/IGS.asp

[leandrenina]

  Sorry I only see your question now. She did seem a bit aneamic at times yes but that's something of the past now. No more symptoms she eats her meals every day without any problem so happy to have a healthy pup. She just turned 3 yrs

[christina]

Hi leandre,
Sorry about ninas problems.
Holly my dog has inflamatory bowel.
Royal canin hypoallergenic she can stomach ok.
And to get her to drink i put cod liver oil caosules in her water and extra virgin olive oil.
She likes the oils so lapps all the water up
I put the tinned hypoallergenic in her kong toy for her to prize out
Makes it more interesting
Recently i have been able to re introduce 3 tablespoons of rice and a small piece of boiled white fish as one of her meals daily and her system tolerating it
I mix a little physillium husk and water into it to help digestion
I also give her some extra virgin coconut oil
It seems to be good for her and she loves the taste
I never deviate from this diet
Probiotics/ prebiotics daily too
And have you tried slippery elm powder ?
I mix that with water into her food when shes struggling
Its a food and nutrient
Hope something ive said may help nina
Christina x
I

[christina]

On the days that nina doesnt eat you could make up a little slippery elm powder mixed with warm.water and try and syringe some into ninas mouth once its lukewarm
Slippery elm coats the stomach lining and is very nutritious
Even add a little honey at least 15+ ( manuka honey) its a food nutrient and very good for stomach disorders and gives a little energy boost also
Cx

[Jo CIMDA]

Hi Leandre

I'm very pleased you have a diagnosis and the treatment is working for Nina.  There seem so many different diseases that affect the digestive system it is often very difficult to achieve a diagnosis. 

Jo

[christina]

Sorry leandra!
When i was reading your posts via my mobile for some reason i missed your last couple of posts and posted advice regards how i cope with hollys digestive problems.
Looking back in i see ..wonderfully ..that ninas problems were resolved!
Thats great!!
Delighted foe you both !:-) x

[Penel CIMDA moderator]

Wow that is fascinating, I've never heard of that condition.  My dog Barley had IBD and had very low cobalamin and folate but it was IBD not a condition like your dog has.  Have you told the breeder?