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Author Topic: Secondary Addison’s disease  (Read 410 times)

Ollspub

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Secondary Addison’s disease
« on: May 26, 2019, 12:37:43 PM »

Hi. We have recently started treating my dog for Secondary Addison’s disease.  He has never had steroids previously.  We had previously been treating him for acid reflux/IBD with no success then he had bloods that showed low cortisol and low eACtH, although he stimmed on an ACTH test.  After any advice anyone can give please. Thank you.
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Catherine

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Re: Secondary Addison’s disease
« Reply #1 on: May 26, 2019, 02:51:53 PM »

Is there anything in particular that you need advice for?

Have you seen here: http://cimda.co.uk/smf/index.php?topic=575.0  and here:?  http://cimda.co.uk/smf/index.php?topic=581.0

Also you can use the search facility on the main page which will come up with lots of posts on "Addison's" that you may find helpful.
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Jo CIMDA

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Re: Secondary Addison’s disease
« Reply #2 on: May 28, 2019, 09:57:23 AM »

Hi and welcome

I presume your dog has atypical Addison's disease where the cortisol levels only are affected?  If this is so then a daily glucocorticoid replacement tablet of prednisolone, 0.1-0.22mg/kg per day (Plumb's Veterinary Drug Handbook, 8th Edition)  will provide all the glucocorticoid hormone needed on a day to day basis, but if there are anticipated times of stress eg., going to see the vet, or when out walking and your dog becomes anxious about something, then you should increase that dose to allow for the fight/flight response that he can no longer produce.  It is always a good idea to take an extra tablet with you when you are walking.

This is an excellent website

http://veterinarymedicine.dvm360.com/cvc-highlights-atypical-addisons-how-will-i-know

The good news is, the prognosis is excellent as long as your dog receives the daily replacement dose.

Jo
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Ollspub

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Re: Secondary Addison’s disease
« Reply #3 on: May 28, 2019, 08:56:39 PM »

He has secondary Addison’s disease his adrenal glands can produce the cortisol but his pituitary gland doesn’t produce the ACTH necessary to tell the adrenal glands to work. Hence he stimmed perfectly on an ACTH test, but has low cortisol and low eACTH.  I’m just looking for anybody with any experience or advice please .  I have been told it is rare. Thank you.
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Jo CIMDA

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Re: Secondary Addison’s disease
« Reply #4 on: May 31, 2019, 08:06:21 PM »

Hi

It is unusual but the prognosis is really good as long as the replacement hormone is given.  An excellent website is DVM 360.  Just put in the subject matter and DVM 360 and you will find really good and reliable veterinary articles.
I hope your dog is responding well to the treatment.

Jo
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Jo CIMDA

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Re: Secondary Addison’s disease
« Reply #5 on: May 31, 2019, 08:21:54 PM »


Dr Mark E Peterson is a brilliant endocrinologist and hit might be worth looking up some of his blogs/articles

https://animalendocrine.com/

Jo
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Ollspub

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Re: Secondary Addison’s disease
« Reply #6 on: June 02, 2019, 08:17:21 AM »

Thank you I will take a look.
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