Secondary Addison’s disease

Started by Ollspub, May 26, 2019, 12:37:43 PM

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Ollspub

Hi. We have recently started treating my dog for Secondary Addison's disease.  He has never had steroids previously.  We had previously been treating him for acid reflux/IBD with no success then he had bloods that showed low cortisol and low eACtH, although he stimmed on an ACTH test.  After any advice anyone can give please. Thank you.

Catherine

Is there anything in particular that you need advice for?

Have you seen here: http://cimda.co.uk/smf/index.php?topic=575.0  and here:?  http://cimda.co.uk/smf/index.php?topic=581.0

Also you can use the search facility on the main page which will come up with lots of posts on "Addison's" that you may find helpful.

Jo CIMDA

Hi and welcome

I presume your dog has atypical Addison's disease where the cortisol levels only are affected?  If this is so then a daily glucocorticoid replacement tablet of prednisolone, 0.1-0.22mg/kg per day (Plumb's Veterinary Drug Handbook, 8th Edition)  will provide all the glucocorticoid hormone needed on a day to day basis, but if there are anticipated times of stress eg., going to see the vet, or when out walking and your dog becomes anxious about something, then you should increase that dose to allow for the fight/flight response that he can no longer produce.  It is always a good idea to take an extra tablet with you when you are walking.

This is an excellent website

http://veterinarymedicine.dvm360.com/cvc-highlights-atypical-addisons-how-will-i-know

The good news is, the prognosis is excellent as long as your dog receives the daily replacement dose.

Jo

Ollspub

He has secondary Addison's disease his adrenal glands can produce the cortisol but his pituitary gland doesn't produce the ACTH necessary to tell the adrenal glands to work. Hence he stimmed perfectly on an ACTH test, but has low cortisol and low eACTH.  I'm just looking for anybody with any experience or advice please .  I have been told it is rare. Thank you.

Jo CIMDA

Hi

It is unusual but the prognosis is really good as long as the replacement hormone is given.  An excellent website is DVM 360.  Just put in the subject matter and DVM 360 and you will find really good and reliable veterinary articles.
I hope your dog is responding well to the treatment.

Jo

Jo CIMDA


Dr Mark E Peterson is a brilliant endocrinologist and hit might be worth looking up some of his blogs/articles

https://animalendocrine.com/

Jo

Ollspub