Just wondering if anyone else has noticed that when their dogs are on high dose prednisone that they can get brittle nails panda has had a nail cut right back to the nail bed because he had a poke injury and his nail was split so vet removed all the nail up to the bed to stop it bleeding he said that panda has brittle nails due to high levels of prednisone have to keep eye on it so it doesn't get infections.