CIMDA

Introductions and other forum info => Tell us a bit about yourself and your dog/s and learn more about the forum. => Topic started by: VivC on July 07, 2019, 10:30:39 AM

Title: Collie newly diagnosed with AIHA
Post by: VivC on July 07, 2019, 10:30:39 AM
Hello, Iíve been pointed in the direction of your forum by a friend. My collie was taken ill last Sunday & quickly diagnosed with AIHA. He had one blood transfusion & his levels have started to rise & remain stable. I am finally bringing him home today but am very nervous about doing the right thing.
Any help advice & guidance will be gratefully received!  :)
Title: Re: Collie newly diagnosed with AIHA
Post by: Catherine on July 07, 2019, 12:45:33 PM
What medication is your dog on? You need to have him on the correct dose as well - not too much and not too little. Here is a good medication protocol:

Immunosuppressive Protocols for Oral Prednisolone in the Dog.
Ref: Clinical Immunology of the Dog & Cat by Michael J Day  Ė Professor of Veterinary Pathology, University of Bristol, UK and WSAVA - Chairman of Scientific Advisory Committee.

This example is based on a dog receiving an induction dose of 1.0mg/kg/q12hrs (every 12 hours)

Dose                Duration (based on clinical effect)

1.0mg/kg/q12h             10-28 days
0.75mg/kg/q12h            10-28 days
0.5mg/kg/q12h             10-28 days
0.25mg/kg/q12h                         10-28 days
0.25mg/kg/q24h                         10-28 days
0.25-0.5mg/kg/ Every other day      at least 21 days
0.25-0.5 mg/kg/ Every third day       at least 21 days

Azathioprine (a cytotoxic drug) can be used in combination with prednisolone at 2mg/kg/24 or 48 hrs and dose gradually reduced, when remission is achieved, over a period of months.
Clinical response to Azathioprine may take up to 6 weeks. (Plumbís Veterinary Drug Handbook)

Don't forget the gastroprotectant!


Have you seen here: http://cimda.co.uk/smf/index.php?topic=11.0 and here: http://cimda.co.uk/smf/index.php?topic=16.0

If there is anything you need to know just ask.
Title: Re: Collie newly diagnosed with AIHA
Post by: Jo CIMDA on July 09, 2019, 11:58:01 AM
Hi an welcome

I am sorry your collie has AIHA.  As Catherine has posted, it is so important that he is on the correct dose of prednisolone, even if he is on other immunosuppressive drugs.

I do hope you see a rise in his red blood cell count very soon.

If you are unsure about anything, please get back to us.

Jo